Introduction: Bioactive Materials are known as substances that can affect living tissue, organisms and cells or their response. These Materials can be used in various fields of medicine and dentistry. Today, the main use of these Materials in dentistry is its use in the treatment of pulp capping, remineralization of teeth in order to restore hard tissue, and anti-caries and antibacterial properties. Some of these substances have the characteristic of alkalines, which can change acidic pH to neutral pH. Also, some others have adhesive properties and chemical bonding, and other features of these Materials include their dimensional stability, biocompatibility, and bioactivity.
Materials and Method: This review was performed by searching among Persian and English sources indexed in Scopus, Pubmed, ISI, and focusing on articles published in recent years.
Results: Bioactive Materials are Materials such as biodentin, polymer Materials with nano-structure in combination with protein-replants, as well as well-known and common Materials that have Bioactive properties such as (mineral trioxide aggregate), calcium hydroxide. Also, in addition to these advantages, various studies have also stated various disadvantages that should be taken into account. These explanations help us to know all the options and Materials in our treatments and make a better choice.
Conclusion: Bioactive substances and their effects can cause changes in different fields of dentistry and provide new solutions to improve the Materials used in dental treatments. However, more invitro and clinical studies are needed to prove the effectiveness of these Materials in the dental Materials syntethis.